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mediastinitis

Advices

≥ 18 years
Priority Medication Remarks
Medication:

amoxicilline + clavulaanzuur iv 1000/200mg 3dd 2 to 6 weeks

+

amoxicilline iv 1000mg 3dd 2 to 6 weeks

Remarks:

SWAB remarks

Na perforatie tr. digestivus: community-accquired. Om en om Augmentin/amoxicilline, dus 3 dd Augmentin 1200 mg en 3 dd amoxicilline 1000 mg

Medication:

cefuroxim iv 1500mg 3dd 2 to 6 weeks

+

metronidazol iv 500mg 3dd 2 weeks

Remarks:

SWAB remarks

Na perforatie tr. digestivus: na manipulatie of ingreep

Medication:

flucloxacilline iv 1000mg 6dd 2 to 6 weeks

or

flucloxacilline iv loading dose 1000mg, 6000mg continuous per 24 hours 2 to 6 weeks

Remarks:

SWAB remarks

Postoperatief na sternotomie

General comments

Op geleide van kweek wordt therapie aangepast

Bij sepsis toevoegen eenmalig tobramycine 7 mg/kg

Sources

  1. Pubmed.gov publication # 31306791

    Pastene B, et al. Mediastinitis in the intensive care unit patient: a narrative review. Clin Microbiol Infect. 2020 Jan;26(1):26-34.

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-8519.6
Updated: 03/28/2023 - 17:21
Status: Published