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imipenem + cilastatine

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DH - Carbapenems -> J01DH51 - Imipenem And Enzyme Inhibitor
Administration category: Free Medicine group: antibacterial Brand name: Tienam

Safety margins

≥ 18 years
Weight ROA Dosage
ROA:
iv
Dosage:
min. 250mg 4 dd to max. 1000mg 4 dd
Comments:

dosisadvies heeft betrekking op imipenem component

Dosage for "I" sensitivity

≥ 18 years
Weight ROA Load Dosage
ROA:
iv
Load:
-
Dosage:
1000mg 4 dd
Comments:

dosisadvies heeft betrekking op imipenem component

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: iv
GFR:
10 - 30
Dosage:
50%
Comments:
normale oplaaddosis
GFR:
<10
Dosage:
50%
Comments:
normale oplaaddosis
Renal elimination: 70%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: normale oplaaddosis, gevolgd door 50% van de normale dosis, 4 dd

Hemo dialysis: normale oplaaddosis, gevolgd door 50% van de normale dosis, 4 dd

CAV / VVHD: normale oplaaddosis, gevolgd door 50% van de normale dosis, 4 dd

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-1495.7
Updated: 01/29/2024 - 17:01
Status: Published

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