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daptomycin

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01X - Other Antibacterials -> J01XX - Other Antibacterials -> J01XX09 - Daptomycin
Administration category: Free Medicine group: antibacterial Brand name: Cubicin

Safety margins

≥ 18 years
Weight ROA Dosage
ROA:
iv
Dosage:
min. 4mg/kg 1 dd
Comments:

Dosering afhankelijk van indicatie, in overleg met internist-infectioloog, arts-microbioloog of ziekenhuisapotheker

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: iv
GFR:
50 - 80
Dosage:
4 mg/kg
Interval:
24 Hours
GFR:
30 - 50
Dosage:
4 mg/kg
Interval:
24 Hours
GFR:
<30
Dosage:
4 mg/kg
Interval:
48 Hours
Renal elimination: 50%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: Normale dosis elke 48 uur.

Hemo dialysis: Normale dosis elke 48 uur, op dialysedagen toedienen na dialyse.

CAV / VVHD: Normale dosis elke 48 uur.

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-1313.5
Updated: 03/07/2023 - 15:54
Status: Published

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